I don't find screens fatiguing. I read long-form digital stuff all the time. I use digital content almost exclusively. I think you will find as the years go by that being able to make the letters bigger is a big, big win. I like to read books, but get sick of holding them. I find the laptop to be my go-to reading device. I had a couple of Kindle devices and other tablets over the years but always go back to the big-old laptop.
There is one paper book I started reading a decade or so. It was a biography of someone I find very interesting, written seventy years or so ago. The book uses a really small font. The only way I could read it was with a headset with magnification that I use for detailed electronics work, and that was not enjoyable. I never finished the book. It still sits on the bookshelf. It might have been the last book I'll ever try to read in paper form. Unfortunately I've never found that book in digital format. Oh well, some things just never make it into digital format.
I've got hundreds of paper books around the house, They're mainly here for nostalgia's sake, and for conversation pieces. Next time I move 99% of them will be donated, if I can find anyone who still wants paper books. Who knows, they make a comeback just like vinyl did.